Anxiety impairs depression remission in partial responders during extended treatment in late-life.
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ABSTRACT:
SUBMITTER: Greenlee A
PROVIDER: S-EPMC2913126 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Publications
Anxiety impairs depression remission in partial responders during extended treatment in late-life.
Greenlee Adam A Karp Jordan F JF Dew Mary Amanda MA Houck Patricia P Andreescu Carmen C Reynolds Charles F CF
Depression and anxiety 20100501 5
<h4>Objectives</h4>More than half of older adults with major depressive disorder require extended treatment because of incomplete response during acute treatment. This study characterizes the effect of anxiety on remission during extended treatment for partial responders.<h4>Methods</h4>Following 6 weeks of escitalopram 10 mg/day+depression care management (DCM), 124 partial responders (Hamilton Rating Scale for Depression (HRSD) scores of 11-14) were randomly assigned to receive extended treatm ...[more]
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