Ontology highlight
ABSTRACT:
SUBMITTER: Fuchs F
PROVIDER: S-EPMC2913390 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Fuchs Florian F Pau Gregoire G Kranz Dominique D Sklyar Oleg O Budjan Christoph C Steinbrink Sandra S Horn Thomas T Pedal Angelika A Huber Wolfgang W Boutros Michael M
Molecular systems biology 20100601
Genetic screens for phenotypic similarity have made key contributions to associating genes with biological processes. With RNA interference (RNAi), highly parallel phenotyping of loss-of-function effects in cells has become feasible. One of the current challenges however is the computational categorization of visual phenotypes and the prediction of biological function and processes. In this study, we describe a combined computational and experimental approach to discover novel gene functions and ...[more]