Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G-protein action.
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ABSTRACT:
SUBMITTER: Pandey S
PROVIDER: S-EPMC2913393 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Publications
Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G-protein action.
Pandey Sona S Wang Rui-Sheng RS Wilson Liza L Li Song S Zhao Zhixin Z Gookin Timothy E TE Assmann Sarah M SM Albert Réka R
Molecular systems biology 20100601
Heterotrimeric G-proteins mediate crucial and diverse signaling pathways in eukaryotes. Here, we generate and analyze microarray data from guard cells and leaves of G-protein subunit mutants of the model plant Arabidopsis thaliana, with or without treatment with the stress hormone, abscisic acid. Although G-protein control of the transcriptome has received little attention to date in any system, transcriptome analysis allows us to search for potentially uncommon yet significant signaling mechani ...[more]
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