Hypnotics with novel modes of action.
Ontology highlight
ABSTRACT:
SUBMITTER: Hoyer D
PROVIDER: S-EPMC7015741 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Publications
Hypnotics with novel modes of action.
Hoyer Daniel D Allen Andrew A Jacobson Laura H LH
British journal of clinical pharmacology 20200117 2
Insomnia and, more generally, lack of sleep are on the rise. Traditionally treated by classical hypnotics, such as benzodiazepines and Z drugs, which both act on the GABA<sub>A</sub> receptor, and other modalities, including nondrug therapies, such as cognitive behavioural therapy, there is a range of new hypnotics which are being developed or have recently received market approval. Suvorexant and the like target the orexin/hypocretin system: they should have less side effects in terms of drug-d ...[more]
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