Ontology highlight
ABSTRACT:
SUBMITTER: Ghersi D
PROVIDER: S-EPMC2913663 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Ghersi Dario D Sanchez Roberto R
Bioinformatics (Oxford, England) 20090929 23
<h4>Unlabelled</h4>SiteHound uses Molecular Interaction Fields (MIFs) produced by EasyMIFs to identify protein structure regions that show a high propensity for interaction with ligands. The type of binding site identified depends on the probe atom used in the MIF calculation. The input to EasyMIFs is a PDB file of a protein structure; the output MIF serves as input to SiteHound, which in turn produces a list of putative binding sites. Extensive testing of SiteHound for the detection of binding ...[more]