Ontology highlight
ABSTRACT:
SUBMITTER: Ngan CH
PROVIDER: S-EPMC3259439 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Ngan Chi-Ho CH Hall David R DR Zerbe Brandon B Grove Laurie E LE Kozakov Dima D Vajda Sandor S
Bioinformatics (Oxford, England) 20111122 2
<h4>Motivation</h4>Binding site identification is a classical problem that is important for a range of applications, including the structure-based prediction of function, the elucidation of functional relationships among proteins, protein engineering and drug design. We describe an accurate method of binding site identification, namely FTSite. This method is based on experimental evidence that ligand binding sites also bind small organic molecules of various shapes and polarity. The FTSite algor ...[more]