Ontology highlight
ABSTRACT:
SUBMITTER: Davidoff AM
PROVIDER: S-EPMC2914477 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Cancer is a disease whose progression is driven by a series of accumulating genetic and epigenetic changes influenced by hereditary factors and the somatic environment. These changes result in individual cells acquiring a phenotype that provides those cells with a survival advantage over surrounding normal cells. Our understanding of the processes that occur in malignant transformation is increasing, with many discoveries in cancer cell biology having been made through the study of childhood tum ...[more]