L-Nebiviololinium chloride dihydrate.

ABSTRACT: The hydro-chloride salt of chiral l-nebivolol {systematic name: (+)-(R,S,S,S)-bis-[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxy-ethyl]ammonium chloride dihydrate}, C(22)H(26)F(2)NO(4) (+)·Cl(-)·2H(2)O, was obtained by chiral liquid chromatography as a dihydrate. The pyran rings adopt half-chair conformations. Hydrogen bonds between the cation, anions and water mol-ecules contribute to the formation of layers parallel to the ac plane.

SUBMITTER: Tuchalski G 

PROVIDER: S-EPMC2915012 | biostudies-literature | 2007 Dec

REPOSITORIES: biostudies-literature