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ABSTRACT:
SUBMITTER: Mermod M
PROVIDER: S-EPMC2916417 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Mermod Mélanie M Mourlane Frédéric F Waltersperger Sandro S Oberholzer Anselm E AE Baumann Ulrich U Solioz Marc M
Journal of bacteriology 20100618 16
In Lactococcus lactis IL1403, 14 genes are under the control of the copper-inducible CopR repressor. This so-called CopR regulon encompasses the CopR regulator, two putative CPx-type copper ATPases, a copper chaperone, and 10 additional genes of unknown function. We addressed here the function of one of these genes, ytjD, which we renamed cinD (copper-induced nitroreductase). Copper, cadmium, and silver induced cinD in vivo, as shown by real-time quantitative PCR. A knockout mutant of cinD was m ...[more]