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Assessment of feeding behavior in laboratory mice.


ABSTRACT: The global obesity epidemic has heightened the need for an improved understanding of how body weight is controlled, and research using mouse models is critical to this effort. In this perspective, we provide a conceptual framework for investigation of feeding behavior in this species, with an emphasis on factors that influence study design, data interpretation, and relevance to feeding behavior in humans. Although we focus on the mouse, the principles presented can be applied to most other animal models. This document represents the current consensus view of investigators from the National Institutes of Health (NIH)-funded Mouse Metabolic Phenotyping Centers (MMPCs).

SUBMITTER: Ellacott KL 

PROVIDER: S-EPMC2916675 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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Assessment of feeding behavior in laboratory mice.

Ellacott Kate L J KL   Morton Gregory J GJ   Woods Stephen C SC   Tso Patrick P   Schwartz Michael W MW  

Cell metabolism 20100701 1


The global obesity epidemic has heightened the need for an improved understanding of how body weight is controlled, and research using mouse models is critical to this effort. In this perspective, we provide a conceptual framework for investigation of feeding behavior in this species, with an emphasis on factors that influence study design, data interpretation, and relevance to feeding behavior in humans. Although we focus on the mouse, the principles presented can be applied to most other anima  ...[more]

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