Ontology highlight
ABSTRACT:
SUBMITTER: Sullivan SP
PROVIDER: S-EPMC2917494 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Sullivan Sean P SP Koutsonanos Dimitrios G DG Del Pilar Martin Maria M Lee Jeong Woo JW Zarnitsyn Vladimir V Choi Seong-O SO Murthy Niren N Compans Richard W RW Skountzou Ioanna I Prausnitz Mark R MR
Nature medicine 20100718 8
Influenza prophylaxis would benefit from a vaccination method enabling simplified logistics and improved immunogenicity without the dangers posed by hypodermic needles. Here we introduce dissolving microneedle patches for influenza vaccination using a simple patch-based system that targets delivery to skin's antigen-presenting cells. Microneedles were fabricated using a biocompatible polymer encapsulating inactivated influenza virus vaccine for insertion and dissolution in the skin within minute ...[more]