Ontology highlight
ABSTRACT:
SUBMITTER: Mathias RA
PROVIDER: S-EPMC2918459 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Mathias Rasika A RA Vergara Candelaria C Gao Li L Rafaels Nicholas N Hand Tracey T Campbell Monica M Bickel Carol C Ivester Priscilla P Sergeant Susan S Barnes Kathleen C KC Chilton Floyd H FH
Journal of lipid research 20100619 9
Long-chain polyunsaturated fatty acids (PUFA) orchestrate immunity and inflammation through their capacity to be converted to potent inflammatory mediators. We assessed associations of FADS gene cluster polymorphisms and fasting serum PUFA concentrations in a fully ascertained, geographically isolated founder population of European descent. Concentrations of 22 PUFAs were determined by gas chromatography, of which ten fatty acids and five ratios defining FADS1 and FADS2 activity were tested for ...[more]