Ontology highlight
ABSTRACT:
SUBMITTER: Di Stefano L
PROVIDER: S-EPMC291854 | biostudies-literature | 2003 Dec
REPOSITORIES: biostudies-literature
Di Stefano Luisa L Jensen Michael Rugaard MR Helin Kristian K
The EMBO journal 20031201 23
The E2F family of transcription factors play an essential role in the regulation of cell cycle progression. In a screen for E2F-regulated genes we identified a novel E2F family member, E2F7. Like the recently identified E2F-like proteins of Arabidopsis, E2F7 has two DNA binding domains and binds to the E2F DNA binding consensus site independently of DP co-factors. Consistent with being an E2F target gene, we found that the expression of E2F7 is cell cycle regulated. Ectopic expression of E2F7 re ...[more]