Ontology highlight
ABSTRACT:
SUBMITTER: Shi A
PROVIDER: S-EPMC2921114 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Shi Anbing A Chen Carlos Chih-Hsiung CC Banerjee Riju R Glodowski Doreen D Audhya Anjon A Rongo Christopher C Grant Barth D BD
Molecular biology of the cell 20100623 16
Caenorhabditis elegans RAB-10 functions in endocytic recycling in polarized cells, regulating basolateral cargo transport in the intestinal epithelia and postsynaptic cargo transport in interneurons. A similar role was found for mammalian Rab10 in MDCK cells, suggesting that a conserved mechanism regulates these related pathways in metazoans. In a yeast two-hybrid screen for binding partners of RAB-10 we identified EHBP-1, a calponin homology domain (CH) protein, whose mammalian homolog Ehbp1 wa ...[more]