Ontology highlight
ABSTRACT:
SUBMITTER: Jordan DM
PROVIDER: S-EPMC2921592 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Jordan Daniel M DM Ramensky Vasily E VE Sunyaev Shamil R SR
Current opinion in structural biology 20100601 3
It is widely anticipated that the coming year will be marked by the complete characterization of DNA sequence of protein-coding regions of thousands of human individuals. A number of existing computational methods use comparative protein sequence analysis and analysis of protein structure to predict the functional effect of coding human alleles. Functional and structural analysis of coding allelic variants can inform various aspects of research on human genetic variation. In population and evolu ...[more]