Ontology highlight
ABSTRACT:
SUBMITTER: Demarco IA
PROVIDER: S-EPMC2921620 | biostudies-literature | 2006 Jul
REPOSITORIES: biostudies-literature
Demarco Ignacio A IA Periasamy Ammasi A Booker Cynthia F CF Day Richard N RN
Nature methods 20060701 7
The mammalian cell nucleus is a dynamic and highly organized structure. Most proteins are mobile within the nuclear compartment, and this mobility reflects transient interactions with chromatin, as well as network interactions with a variety of protein partners. To study these dynamic processes in living cells, we developed an imaging method that combines the photoactivated green fluorescent protein (PA-GFP) and fluorescence resonance energy transfer (FRET) microscopy. We used this new method, p ...[more]