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A bioorthogonal chemistry strategy for probing protein lipidation in live cells.


ABSTRACT: We report a chemical lipidation model for the study of protein lipidations in vitro and in live mammalian cells based on a bioorthogonal, photoinduced tetrazole-alkene cycloaddition reaction.

SUBMITTER: Song W 

PROVIDER: S-EPMC2922461 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature

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A bioorthogonal chemistry strategy for probing protein lipidation in live cells.

Song Wenjiao W   Yu Zhipeng Z   Madden Michael M MM   Lin Qing Q  

Molecular bioSystems 20100430 9


We report a chemical lipidation model for the study of protein lipidations in vitro and in live mammalian cells based on a bioorthogonal, photoinduced tetrazole-alkene cycloaddition reaction. ...[more]

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