Ontology highlight
ABSTRACT:
SUBMITTER: Bumb A
PROVIDER: S-EPMC2922462 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Bumb Ambika A Brechbiel Martin W MW Choyke Peter P
Acta radiologica (Stockholm, Sweden : 1987) 20100901 7
Magnetic resonance imaging (MRI) is a powerful imaging modality that can provide an assessment of function or molecular expression in tandem with anatomic detail. Over the last 20-25 years, a number of gadolinium-based MR contrast agents have been developed to enhance signal by altering proton relaxation properties. This review explores a range of these agents from small molecule chelates, such as Gd-DTPA and Gd-DOTA, to macromolecular structures composed of albumin, polylysine, polysaccharides ...[more]