Oxidase-like activity of polymer-coated cerium oxide nanoparticles.
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ABSTRACT:
SUBMITTER: Asati A
PROVIDER: S-EPMC2923475 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Publications
Oxidase-like activity of polymer-coated cerium oxide nanoparticles.
Asati Atul A Santra Santimukul S Kaittanis Charalambos C Nath Sudip S Perez J Manuel JM
Angewandte Chemie (International ed. in English) 20090101 13
Inorganic enzyme? Ceria nanoparticles exhibit unique oxidase-like activity at acidic pH values. These redox catalysts can be used in immunoassays (ELISA) when modified with targeting ligands (see picture; light blue and yellow structures are nanoparticles with attached ligands). This modification allows both for binding and for detection by the catalytic oxidation of sensitive colorimetric dyes (e.g. TMB). ...[more]
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