Ontology highlight
ABSTRACT:
SUBMITTER: Kim JY
PROVIDER: S-EPMC2924440 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Kim Jin Young JY Lee Kwang Hee KH Shim Myoung Sup MS Shin Hyein H Xu Xue-Ming XM Carlson Bradley A BA Hatfield Dolph L DL Lee Byeong Jae BJ
Biochemical and biophysical research communications 20100522 1
Selenophosphate synthetase 1 (SPS1) is an essential cellular gene in higher eukaryotes. Five alternative splice variants of human SPS1 (major type, DeltaE2, DeltaE8, +E9, +E9a) were identified wherein +E9 and +E9a make the same protein. The major type was localized in both the nuclear and plasma membranes, and the others in the cytoplasm. All variants form homodimers, and in addition, the major type forms a heterodimer with DeltaE2, and DeltaE8 with +E9. The level of expression of each splice va ...[more]