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Design and investigation of a series of rhodamine-based fluorescent probes for optical measurements of pH.

ABSTRACT: A series of structurally similar fluorescent probes (1-4), synthesized from rhodamine B, were designed to optically measure pH. Each probe had a unique "off-on" response as the solution went from basic to acidic. Probes 1-3 exhibited a spirocyclic quenching of the pyronin B fluorophore, whereas probe 4 was quenched by PET from the amine moiety.

SUBMITTER: Best QA

PROVIDER: S-EPMC2925113 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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Design and investigation of a series of rhodamine-based fluorescent probes for optical measurements of pH.

Best Quinn A QA Xu Ruisong R McCarroll Matthew E ME Wang Lichang L Dyer Daniel J DJ

Organic letters 20100701 14

A series of structurally similar fluorescent probes (1-4), synthesized from rhodamine B, were designed to optically measure pH. Each probe had a unique "off-on" response as the solution went from basic to acidic. Probes 1-3 exhibited a spirocyclic quenching of the pyronin B fluorophore, whereas probe 4 was quenched by PET from the amine moiety. ...[more]

PMID: 20572677

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