Ontology highlight
ABSTRACT:
SUBMITTER: Poulsen C
PROVIDER: S-EPMC2925521 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Poulsen Christian C Akhter Yusuf Y Jeon Amy Hye-Won AH Schmitt-Ulms Gerold G Meyer Helmut E HE Stefanski Anja A Stühler Kai K Wilmanns Matthias M Song Young-Hwa YH
Molecular systems biology 20100701
Mycobacteria use a unique system for covalently modifying proteins based on the conjugation of a small protein, referred to as prokaryotic ubiquitin-like protein (PUP). In this study, we report a proteome-wide analysis of endogenous pupylation targets in the model organism Mycobacterium smegmatis. On affinity capture, a total of 243 candidate pupylation targets were identified by two complementary proteomics approaches. For 41 of these protein targets, direct evidence for a total of 48 lysine-me ...[more]