Ontology highlight
ABSTRACT:
SUBMITTER: Burr ML
PROVIDER: S-EPMC2927647 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Burr Marian L ML Naseem Haris H Hinks Anne A Eyre Steve S Gibbons Laura J LJ Bowes John J Wilson Anthony G AG Maxwell James J Morgan Ann W AW Emery Paul P Steer Sophia S Hocking Lynne L Reid David M DM Wordsworth Paul P Harrison Pille P Thomson Wendy W Worthington Jane J Barton Anne A
Annals of the rheumatic diseases 20090525 4
<h4>Background</h4>Polymorphisms of the peptidylarginine deiminase type 4 (PADI4) gene confer susceptibility to rheumatoid arthritis (RA) in East Asian people. However, studies in European populations have produced conflicting results. This study explored the association of the PADI4 genotype with RA in a large UK Caucasian population.<h4>Methods</h4>The PADI4_94 (rs2240340) single nucleotide polymorphism (SNP) was directly genotyped in a cohort of unrelated UK Caucasian patients with RA (n=3732 ...[more]