Ontology highlight
ABSTRACT:
SUBMITTER: Shang WH
PROVIDER: S-EPMC2928500 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Shang Wei-Hao WH Hori Tetsuya T Toyoda Atsushi A Kato Jun J Popendorf Kris K Sakakibara Yasubumi Y Fujiyama Asao A Fukagawa Tatsuo T
Genome research 20100609 9
The centromere is essential for faithful chromosome segregation by providing the site for kinetochore assembly. Although the role of the centromere is conserved throughout evolution, the DNA sequences associated with centromere regions are highly divergent among species and it remains to be determined how centromere DNA directs kinetochore formation. Despite the active use of chicken DT40 cells in studies of chromosome segregation, the sequence of the chicken centromere was unclear. Here, we per ...[more]