Ontology highlight
ABSTRACT:
SUBMITTER: Schoell ED
PROVIDER: S-EPMC2930255 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Schoell Eszter D ED Bingel Ulrike U Eippert Falk F Yacubian Juliana J Christiansen Kerrin K Andresen Hilke H May Arne A Buechel Christian C
PloS one 20100827 8
The endogenous opioid system represents one of the principal systems in the modulation of pain. This has been demonstrated in studies of placebo analgesia and stress-induced analgesia, where anti-nociceptive activity triggered by pain itself or by cognitive states is blocked by opioid antagonists. The aim of this study was to characterize the effect of opioid receptor blockade on the physiological processing of painful thermal stimulation in the absence of cognitive manipulation. We therefore me ...[more]