Dataset Information

RankProdIt: A web-interactive Rank Products analysis tool.

ABSTRACT:

Background

The first objective of a DNA microarray experiment is typically to generate a list of genes or probes that are found to be differentially expressed or represented (in the case of comparative genomic hybridizations and/or copy number variation) between two conditions or strains. Rank Products analysis comprises a robust algorithm for deriving such lists from microarray experiments that comprise small numbers of replicates, for example, less than the number required for the commonly used t-test. Currently, users wishing to apply Rank Products analysis to their own microarray data sets have been restricted to the use of command line-based software which can limit its usage within the biological community.

Findings

Here we have developed a web interface to existing Rank Products analysis tools allowing users to quickly process their data in an intuitive and step-wise manner to obtain the respective Rank Product or Rank Sum, probability of false prediction and p-values in a downloadable file.

Conclusions

The online interactive Rank Products analysis tool RankProdIt, for analysis of any data set containing measurements for multiple replicated conditions, is available at: http://strep-microarray.sbs.surrey.ac.uk/RankProducts.

SUBMITTER: Laing E

PROVIDER: S-EPMC2930644 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature

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Publications

RankProdIt: A web-interactive Rank Products analysis tool.

Laing Emma E Smith Colin P CP

BMC research notes 20100806

<h4>Background</h4>The first objective of a DNA microarray experiment is typically to generate a list of genes or probes that are found to be differentially expressed or represented (in the case of comparative genomic hybridizations and/or copy number variation) between two conditions or strains. Rank Products analysis comprises a robust algorithm for deriving such lists from microarray experiments that comprise small numbers of replicates, for example, less than the number required for the comm ...[more]

PMID: 20691047

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Dataset Information

RankProdIt: A web-interactive Rank Products analysis tool.

Background

Findings

Conclusions

Publications

RankProdIt: A web-interactive Rank Products analysis tool.

Similar Datasets

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