Ontology highlight
ABSTRACT:
SUBMITTER: Mehlert A
PROVIDER: S-EPMC2935967 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Mehlert Angela A Sullivan Lauren L Ferguson Michael A J MA
Molecular and biochemical parasitology 20100615 1
Following a switch from variant surface glycoprotein MITat1.4 to variant surface glycoprotein MITat1.8 expression by Lister strain 427 Trypanosoma brucei brucei parasites, the latter uncharacterized variant surface glycoprotein was analysed. Variant surface glycoprotein MITat1.8 was found to be a disulphide-linked homodimer, containing a complex N-linked glycan at Asn58 and a glycosylphosphatidylinositol membrane anchor attached to Asp419. Mass spectrometric analyses demonstrated that the N-glyc ...[more]