Ontology highlight
ABSTRACT:
SUBMITTER: Li C
PROVIDER: S-EPMC2937868 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Li Cong C Tan Tianwei T Zhang Haiyang H Feng Wei W
The Journal of biological chemistry 20100703 37
The conformational stability and activity of Candida antarctica lipase B (CALB) in the polar and nonpolar organic solvents were investigated by molecular dynamics and quantum mechanics/molecular mechanics simulations. The conformation change of CALB in the polar and nonpolar solvents was examined in two aspects: the overall conformation change of CALB and the conformation change of the active site. The simulation results show that the overall conformation of CALB is stable in the organic solvent ...[more]