Ontology highlight
ABSTRACT:
SUBMITTER: Fuentes-Duculan J
PROVIDER: S-EPMC2939947 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Fuentes-Duculan Judilyn J Suárez-Fariñas Mayte M Zaba Lisa C LC Nograles Kristine E KE Pierson Katherine C KC Mitsui Hiroshi H Pensabene Cara A CA Kzhyshkowska Julia J Krueger James G JG Lowes Michelle A MA
The Journal of investigative dermatology 20100617 10
Macrophages are important cells of the innate immune system, and their study is essential to gain greater understanding of the inflammatory nature of psoriasis. We used immunohistochemistry and double-label immunofluorescence to characterize CD163(+) macrophages in psoriasis. Dermal macrophages were increased in psoriasis compared with normal skin and were identified by CD163, RFD7, CD68, lysosomal-associated membrane protein 2 (LAMP2), stabilin-1, and macrophage receptor with collagenous struct ...[more]