Ontology highlight
ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC2944534 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Wang Shuning S Huang Haiyan H Moll Johanna J Thauer Rudolf K RK
Journal of bacteriology 20100730 19
It was recently found that the cytoplasmic butyryl-coenzyme A (butyryl-CoA) dehydrogenase-EtfAB complex from Clostridium kluyveri couples the exergonic reduction of crotonyl-CoA to butyryl-CoA with NADH and the endergonic reduction of ferredoxin with NADH via flavin-based electron bifurcation. We report here on a second cytoplasmic enzyme complex in C. kluyveri capable of energetic coupling via this novel mechanism. It was found that the purified iron-sulfur flavoprotein complex NfnAB couples th ...[more]