Ontology highlight
ABSTRACT:
SUBMITTER: Wu X
PROVIDER: S-EPMC2944798 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Wu Xuesen X Dong Hua H Luo Li L Zhu Yun Y Peng Gang G Reveille John D JD Xiong Momiao M
PLoS genetics 20100923 9
Although great progress in genome-wide association studies (GWAS) has been made, the significant SNP associations identified by GWAS account for only a few percent of the genetic variance, leading many to question where and how we can find the missing heritability. There is increasing interest in genome-wide interaction analysis as a possible source of finding heritability unexplained by current GWAS. However, the existing statistics for testing interaction have low power for genome-wide interac ...[more]