Genomic imprinting in diabetes.
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ABSTRACT:
SUBMITTER: Mitchell BD
PROVIDER: S-EPMC2945012 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Publications
Genomic imprinting refers to a class of transmissible genetic effects in which the expression of the phenotype in the offspring depends on the parental origin of the transmitted allele. The DNA from one parent may be epigenetically modified so that only a single allele of the imprinted gene is expressed in the offspring. Although imprinting has an important role in the regulation of growth and development through its role in regulating gene expression, its contribution to susceptibility to commo ...[more]
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