Ontology highlight
ABSTRACT:
SUBMITTER: Amorde SM
PROVIDER: S-EPMC2947323 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Tetrahedron 20090401 16
A novel iminium ion cascade reaction has been developed that allows for the stereoselective synthesis of a variety of substituted aza-fused bicycles. The combination of amino allylsilanes and aldehydes (or ketones) was used to synthesize a number of quinolizidines and indolizidines in an one-pot reaction sequence. This technology has been used to effect the facile syntheses of several indolizidine and quinolizidine natural products including, (±)-epilupinine, (±)-tashiromine, and (-)-epimyrtine. ...[more]