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Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines.

ABSTRACT: A [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol.

SUBMITTER: Provoost OY

PROVIDER: S-EPMC1810302 | biostudies-literature | 2007 Feb

REPOSITORIES: biostudies-literature

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Pd-catalysed [3 + 3] annelations in the stereoselective synthesis of indolizidines.

Provoost Olivier Y OY Hazelwood Andrew J AJ Harrity Joseph P A JP

Beilstein journal of organic chemistry 20070208

A [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol. ...[more]

PMID: 17288604

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