Ontology highlight
ABSTRACT:
SUBMITTER: Perez-Victoria FJ
PROVIDER: S-EPMC2947474 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Pérez-Victoria F Javier FJ Schindler Christina C Magadán Javier G JG Mardones Gonzalo A GA Delevoye Cédric C Romao Maryse M Raposo Graça G Bonifacino Juan S JS
Molecular biology of the cell 20100804 19
The Golgi-associated retrograde protein (GARP) complex mediates tethering and fusion of endosome-derived transport carriers to the trans-Golgi network (TGN). In the yeast Saccharomyces cerevisiae, GARP comprises four subunits named Vps51p, Vps52p, Vps53p, and Vps54p. Orthologues of the GARP subunits, except for Vps51p, have been identified in all other eukaryotes. A yeast two-hybrid screen of a human cDNA library yielded a phylogenetically conserved protein, Ang2/Fat-free, which interacts with h ...[more]