Ontology highlight
ABSTRACT:
SUBMITTER: Mikkelsen TS
PROVIDER: S-EPMC2950833 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Cell 20101001 1
We report the generation and comparative analysis of genome-wide chromatin state maps, PPARγ and CTCF localization maps, and gene expression profiles from murine and human models of adipogenesis. The data provide high-resolution views of chromatin remodeling during cellular differentiation and allow identification of thousands of putative preadipocyte- and adipocyte-specific cis-regulatory elements based on dynamic chromatin signatures. We find that the specific locations of most such elements d ...[more]