Ontology highlight
ABSTRACT:
SUBMITTER: Reese E
PROVIDER: S-EPMC2951702 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Bioinformation 20100430 10
A new classification scheme based on the melting profile of DNA sequences simulated thermal melting profiles. This method was applied in the classification of (a) several species of mammalian - β globin and (b) α-chain class II MHC genes. Comparison of the thermal melting profile with the molecular phylogenetic trees constructed using the sequences shows that the melting temperature based approach is able to reproduce most of the major features of the sequence based evolutionary tree. Melting pr ...[more]