Ontology highlight
ABSTRACT:
SUBMITTER: Ramboarina S
PROVIDER: S-EPMC2952246 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Ramboarina Stéphanie S Garnett James A JA Zhou Meixian M Li Yuebin Y Peng Zhixiang Z Taylor Jonathan D JD Lee Wei-Chao WC Bodey Andrew A Murray James W JW Alguel Yilmaz Y Bergeron Julien J Bardiaux Benjamin B Sawyer Elizabeth E Isaacson Rivka R Tagliaferri Camille C Cota Ernesto E Nilges Michael M Simpson Peter P Ruiz Teresa T Wu Hui H Matthews Stephen S
The Journal of biological chemistry 20100628 42
The serine-rich repeat family of fimbriae play important roles in the pathogenesis of streptococci and staphylococci. Despite recent attention, their finer structural details and precise adhesion mechanisms have yet to be determined. Fap1 (Fimbriae-associated protein 1) is the major structural subunit of serine-rich repeat fimbriae from Streptococcus parasanguinis and plays an essential role in fimbrial biogenesis, adhesion, and the early stages of dental plaque formation. Combining multidiscipl ...[more]