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A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2?A resolution.


ABSTRACT: BT1062 from Bacteroides thetaiotaomicron is a homolog of Mfa2 (PGN0288 or PG0179), which is a component of the minor fimbriae in Porphyromonas gingivalis. The crystal structure of BT1062 revealed a conserved fold that is widely adopted by fimbrial components.

SUBMITTER: Xu Q 

PROVIDER: S-EPMC2954217 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

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A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution.

Xu Qingping Q   Abdubek Polat P   Astakhova Tamara T   Axelrod Herbert L HL   Bakolitsa Constantina C   Cai Xiaohui X   Carlton Dennis D   Chen Connie C   Chiu Hsiu Ju HJ   Chiu Michelle M   Clayton Thomas T   Das Debanu D   Deller Marc C MC   Duan Lian L   Ellrott Kyle K   Farr Carol L CL   Feuerhelm Julie J   Grant Joanna C JC   Grzechnik Anna A   Han Gye Won GW   Jaroszewski Lukasz L   Jin Kevin K KK   Klock Heath E HE   Knuth Mark W MW   Kozbial Piotr P   Krishna S Sri SS   Kumar Abhinav A   Marciano David D   McMullan Daniel D   Miller Mitchell D MD   Morse Andrew T AT   Nigoghossian Edward E   Nopakun Amanda A   Okach Linda L   Puckett Christina C   Reyes Ron R   Sefcovic Natasha N   Tien Henry J HJ   Trame Christine B CB   van den Bedem Henry H   Weekes Dana D   Wooten Tiffany T   Yeh Andrew A   Zhou Jiadong J   Hodgson Keith O KO   Wooley John J   Elsliger Marc Andre MA   Deacon Ashley M AM   Godzik Adam A   Lesley Scott A SA   Wilson Ian A IA  

Acta crystallographica. Section F, Structural biology and crystallization communications 20100706 Pt 10


BT1062 from Bacteroides thetaiotaomicron is a homolog of Mfa2 (PGN0288 or PG0179), which is a component of the minor fimbriae in Porphyromonas gingivalis. The crystal structure of BT1062 revealed a conserved fold that is widely adopted by fimbrial components. ...[more]

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