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4-(4-Fluoro-phen-yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one.

ABSTRACT: The crystal structure of the title compound, C(15)H(11)FN(2)O(3), was determined as part of a study on the biological activity of isoxazolone derivatives as p38 mitogen-activated protein kinase (MAPK) inhibitors. The dihedral angles between rings are isoxazole/benzene = 55.0?(3)°, isoxazole/pyridine = 33.8?(2)° and benzene/pyridine = 58.1?(2)°.

SUBMITTER: Margutti S

PROVIDER: S-EPMC2960186 | biostudies-literature | 2008

REPOSITORIES: biostudies-literature

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4-(4-Fluoro-phen-yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one.

Margutti Simona S Schollmeyer Dieter D Laufer Stefan S

Acta crystallographica. Section E, Structure reports online 20080123 Pt 2

The crystal structure of the title compound, C(15)H(11)FN(2)O(3), was determined as part of a study on the biological activity of isoxazolone derivatives as p38 mitogen-activated protein kinase (MAPK) inhibitors. The dihedral angles between rings are isoxazole/benzene = 55.0 (3)°, isoxazole/pyridine = 33.8 (2)° and benzene/pyridine = 58.1 (2)°. ...[more]

PMID: 21201524

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