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1-Benzhydryl-4-(4-chloro-phenyl-sulfonyl)piperazine.

ABSTRACT: The title compound, C(23)H(23)ClN(2)O(2)S, was synthesized by the nucleophilic substitution of 1-benzhydrylpiperazine with 4-chloro-phenyl-sulfonyl chloride. The piperazine ring is in a chair conformation. The geometry around the S atom is that of a distorted tetra-hedron. There is a large range of bond angles around the piperazine N atoms. The dihedral angle between the least-squares plane (p1) defined by the four coplanar C atoms of the piperazine ring and the benzene ring is 81.6?(1)°. The dihedral angles between p1 and the phenyl rings are 76.2?(1) and 72.9?(2)°. The two phenyl rings make a dihedral angle of 65.9?(1)°. Intramolecular C-H?O hydrogen bonds are present.

SUBMITTER: Girisha HR

PROVIDER: S-EPMC2960354 | biostudies-literature | 2008 Jan

REPOSITORIES: biostudies-literature

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1-Benzhydryl-4-(4-chloro-phenyl-sulfonyl)piperazine.

Girisha H R HR Naveen S S Vinaya K K Sridhar M A MA Shashidhara Prasad J J Rangappa K S KS

Acta crystallographica. Section E, Structure reports online 20080104 Pt 2

The title compound, C(23)H(23)ClN(2)O(2)S, was synthesized by the nucleophilic substitution of 1-benzhydrylpiperazine with 4-chloro-phenyl-sulfonyl chloride. The piperazine ring is in a chair conformation. The geometry around the S atom is that of a distorted tetra-hedron. There is a large range of bond angles around the piperazine N atoms. The dihedral angle between the least-squares plane (p1) defined by the four coplanar C atoms of the piperazine ring and the benzene ring is 81.6 (1)°. The di ...[more]

PMID: 21201390

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