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Rac-2-Hydroxy-2,8-dimethyl-4-morpho-linoethyl-1-thia-4-aza-spiro-[4.5]decan-3-one.

ABSTRACT: The title compound, C(16)H(28)N(2)O(3)S, is dimerized by inversion symmetry-related inter-molecular O-H?N hydrogen bonding, forming an R(2) (2)(16) motif. The dimers are also linked through inter-molecular C-H?O hydrogen bonding. The compound is chiral with a stereogenic centre located in the thia-zole ring, but in the crystal structure it forms a racemate. The thia-zole ring has an envelope conformation, while the cyclo-hexane and morpholine rings adopt chair conformations.

SUBMITTER: Akkurt M

PROVIDER: S-EPMC2962193 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature

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rac-2-Hydroxy-2,8-dimethyl-4-morpho-linoethyl-1-thia-4-aza-spiro-[4.5]decan-3-one.

Akkurt Mehmet M Yalçın Serife Pınar SP Klip Nalan Terzioğlu NT Büyükgüngör Orhan O

Acta crystallographica. Section E, Structure reports online 20080723 Pt 8

The title compound, C(16)H(28)N(2)O(3)S, is dimerized by inversion symmetry-related inter-molecular O-H⋯N hydrogen bonding, forming an R(2) (2)(16) motif. The dimers are also linked through inter-molecular C-H⋯O hydrogen bonding. The compound is chiral with a stereogenic centre located in the thia-zole ring, but in the crystal structure it forms a racemate. The thia-zole ring has an envelope conformation, while the cyclo-hexane and morpholine rings adopt chair conformations. ...[more]

PMID: 21203274

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4-(Pyrimidin-2-yl)-1-thia-4-aza-spiro-[4.5]decan-3-one.

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6-Benzyl-3-(1,4-dioxaspiro-[4.5]decan-2-yl)-8,8-dimethyl-1-oxa-2,6-diaza-spiro-[4.4]non-2-ene-7,9-dione.

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