Ontology highlight
ABSTRACT:
SUBMITTER: Dierksen GA
PROVIDER: S-EPMC2964411 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Dierksen Gregory A GA Skehan Maureen E ME Khan Muhammad A MA Jeng Jed J Nandigam R N Kaveer RN Becker John A JA Kumar Ashok A Neal Krista L KL Betensky Rebecca A RA Frosch Matthew P MP Rosand Jonathan J Johnson Keith A KA Viswanathan Anand A Salat David H DH Greenberg Steven M SM
Annals of neurology 20101001 4
Advanced cerebrovascular β-amyloid deposition (cerebral amyloid angiopathy, CAA) is associated with cerebral microbleeds, but the precise relationship between CAA burden and microbleeds is undefined. We used T2*-weighted magnetic resonance imaging (MRI) and noninvasive amyloid imaging with Pittsburgh Compound B (PiB) to analyze the spatial relationship between CAA and microbleeds. On coregistered positron emission tomography (PET) and MRI images, PiB retention was increased at microbleed sites c ...[more]