Ontology highlight
ABSTRACT:
SUBMITTER: Salvador LA
PROVIDER: S-EPMC2965599 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Salvador Lilibeth A LA Paul Valerie J VJ Luesch Hendrik H
Journal of natural products 20100901 9
A Phormidium spp. collection from Key West, Florida, afforded caylobolide B (1), an analogue of the known macrolactone caylobolide A, previously isolated from a Lyngbya majuscula collection from the Bahamas. The planar structure of 1 was determined using NMR and MS experiments. The relative configuration for subunits C7-C9 and C25-C29 was assigned using Kishi's Universal NMR Database. Caylobolide B (1) displayed cytotoxic activity against HT29 colorectal adenocarcinoma and HeLa cervical carcinom ...[more]