Ontology highlight
ABSTRACT:
SUBMITTER: Saez ME
PROVIDER: S-EPMC2967537 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Sáez María E ME González-Pérez Antonio A Martínez-Larrad María T MT Gayán Javier J Real Luis M LM Serrano-Ríos Manuel M Ruiz Agustín A
BMC medical genetics 20101014
<h4>Background</h4>Altered lipid profile, and in particular low HDL and high triglyceride (TG) plasma levels, are within the major determinants of cardiovascular diseases. The identification of quantitative trait loci (QTL) affecting these lipid levels is a relevant issue for predictive purposes. The WWOX gene has been recently associated with HDL levels. This gene is located at chromosome 16q23, a region previously linked to familial combined hyperlipidemia (FCHL) and HDL. Our objective is to p ...[more]