Ontology highlight
ABSTRACT:
SUBMITTER: Flaquer A
PROVIDER: S-EPMC4422732 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Flaquer Antònia A Rospleszcz Susanne S Reischl Eva E Zeilinger Sonja S Prokisch Holger H Meitinger Thomas T Meisinger Christa C Peters Annette A Waldenberger Melanie M Grallert Harald H Strauch Konstantin K
PloS one 20150506 5
It has been suggested that mitochondrial dysfunction has an influence on lipid metabolism. The fact that mitochondrial defects can be accumulated over time as a normal part of aging may explain why cholesterol levels often are altered with age. To test the hypothesis whether mitochondrial variants are associated with lipid profile (total cholesterol, LDL, HDL, and triglycerides) we analyzed a total number of 978 mitochondrial single nucleotide polymorphisms (mtSNPs) in a sample of 2,815 individu ...[more]