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2-(4-Fluoro-anilino)-3-(2-hydroxy-ethyl)quinazolin-4(3H)-one.

ABSTRACT: The mol-ecular and crystal structures of the title compound, C(16)H(14)FN(3)O(2), are stabilized by intra-molecular N-H?O and inter-molecular O-H?O hydrogen bonds. The existence of non-classical intra-molecular C-H?N hydrogen bonds provides a dihedral angle between the fluoro-substituted benzene and pyrimidinone rings of 7.9?(1)°.

SUBMITTER: Zhang Q

PROVIDER: S-EPMC2968625 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature

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2-(4-Fluoro-anilino)-3-(2-hydroxy-ethyl)quinazolin-4(3H)-one.

Zhang Qian Q Jiao Yuan-Hong YH Liu Bin B Chen Xue-Mei XM Ruan Min M Xu Ling-Hua LH

Acta crystallographica. Section E, Structure reports online 20090228 Pt 3

The mol-ecular and crystal structures of the title compound, C(16)H(14)FN(3)O(2), are stabilized by intra-molecular N-H⋯O and inter-molecular O-H⋯O hydrogen bonds. The existence of non-classical intra-molecular C-H⋯N hydrogen bonds provides a dihedral angle between the fluoro-substituted benzene and pyrimidinone rings of 7.9 (1)°. ...[more]

PMID: 21582287

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