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1-[(6-Chloro-3-pyrid-yl)meth-yl]-N-(4-ethoxy-phen-yl)-3-phenyl-1H-pyrazole-5-carboxamide.

ABSTRACT: In the title compound, C(24)H(21)ClN(4)O(2), the pyrazole ring makes dihedral angles of 7.70 (11), 89.17 (11) and 40.68 (11)° with the phenyl, pyridine and ethoxy-phenyl rings, respectively. There are some intra-molecular C-H⋯O and C-H⋯π bonds giving rigidity to the mol-ecule, while weak inter-molecular N-H⋯N and C-H⋯π hydrogen bonds link the mol-ecules into a two-dimensional structure.

SUBMITTER: Tang Z

PROVIDER: S-EPMC2968942 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature

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1-[(6-Chloro-3-pyrid-yl)meth-yl]-N-(4-ethoxy-phen-yl)-3-phenyl-1H-pyrazole-5-carboxamide.

Tang Zheng Z Ding Xiao-Liang XL Dong Wen-Liang WL Zhao Bao-Xiang BX

Acta crystallographica. Section E, Structure reports online 20090325 Pt 4

In the title compound, C(24)H(21)ClN(4)O(2), the pyrazole ring makes dihedral angles of 7.70 (11), 89.17 (11) and 40.68 (11)° with the phenyl, pyridine and ethoxy-phenyl rings, respectively. There are some intra-molecular C-H⋯O and C-H⋯π bonds giving rigidity to the mol-ecule, while weak inter-molecular N-H⋯N and C-H⋯π hydrogen bonds link the mol-ecules into a two-dimensional structure. ...[more]

PMID: 21582579

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N-[4-Chloro-2-methyl-6-(N-methyl-car-bam-oyl)phen-yl]-1-(3-chloro-2-pyrid-yl)-3-trifluoro-meth-yl-1H-pyrazole-5-carboxamide.

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Project description:In the title compound, C(31)H(24)Cl(2)N(2)S(2), the pyrazole ring adopts planar conformation with a maximum deviation of 0.002 (2) Å. The chloro-phenyl rings are twisted out of the plane of the pyrazole ring by 75.1 (1) and 39.5 (1)°. The crystal packing is controlled by weak intermolecular C-H⋯π interactions.

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