5-Chloro-N-{4-oxo-2-[4-(trifluoro-meth-yl)phen-yl]-1,3-thia-zolidin-3-yl}-3-phenyl-1H-indole-2-carboxamide.

ABSTRACT: In the title compound, C(25)H(17)ClF(3)N(3)O(2)S, the five-membered 1,3-thia-zolidine ring adopts a twist conformation. The three F atoms of the CF(3) group are disordered over two sets of sites with refined occupancies of 0.542?(18) and 0.458?(18). In the nine-membered 1H-indoline ring system, the 1H-pyrrole ring forms a dihedral angle of 4.7?(2)° with the benzene ring, while it is twisted at an angle of 46.5?(2)° with respect to the attached phenyl ring. The dihedral angle between the phenyl and trifluoro-methyl-substituted benzene rings is 56.0?(2)°. In the crystal, N-H?O hydrogen bonds connect the mol-ecules into a three-dimensional network. In addition, weak C-H?O hydrogen bonds and weak C-H?? inter-actions are observed.

SUBMITTER: Akkurt M 

PROVIDER: S-EPMC3470337 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature