Ontology highlight
ABSTRACT:
SUBMITTER: Laukens D
PROVIDER: S-EPMC2970560 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Laukens Debby D Georges Michel M Libioulle Cécile C Sandor Cynthia C Mni Myriam M Vander Cruyssen Bert B Peeters Harald H Elewaut Dirk D De Vos Martine M
PloS one 20101102 11
<h4>Background</h4>A multicenter genome-wide association scan for Crohn's Disease (CD) has recently reported 40 CD susceptibility loci, including 29 novel ones (19 significant and 10 putative). To gain insight into the genetic overlap between CD and ankylosing spondylitis (AS), these markers were tested for association in AS patients.<h4>Principal findings</h4>Two previously established associations, namely with the MHC and IL23R loci, were confirmed. In addition, rs2872507, which maps to a locu ...[more]